Looked at as feasible therapeutic medicine Timothy Leary and also Richard Alpert consumption high in the 1960s-1970s component of the “hippie” society to discover their “true” selves. Decreased in the 1980s Cocaine became the drug of selection Used again in the beforehand 1990s shift to club/rave psychedelic drugs Terence McKenna "Timothy Leary of the 90s"Believed that psychedelics permit us to check out reach true pundit vision important to carry out the appropriate things in this world. Permit us come “decondition” ourselves.


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Etherogens •“Generating the ______ ________”. Commonly used in _______ ________. Generate ________, _________…•_______, ______, ________, _____, ______
Etherogens •“Generating the devine within”. Typically used in spiritual ceremonies. Generate transcendence, revelations…•LSD, Peyote, pysosibin, DMT, Salvia
Dissociatives Block the _________ mind kind the ________.......Lead to ________ (loss of _______), _______, _________________ ________, ________ (used as anethetic)
Dissociatives Block the aware mind kind the remainder of other parts the the brain.Lead to catalepsy (loss the sensitization), amnesia, anesthesiaNitrous oxide, Ketamine (used together anethetic)
Classification based upon receptor activation:4 main varieties based ~ above receptor duty __________ hallucinogens -Methylated _________ - _______________ _________ _________
Classification based on receptor activation:4 main varieties based top top receptor role Serotonergic hallucinogens -Methylated amphetamines - Anticholinergic - (Acetylcholine) Dissociative anesthetics:
Classification based upon receptor activation:4 main species based top top receptor duty Serotonergic hallucinogens - Chemically comparable to _________ - __________ receptor _________ Methylated Amphetamines - Chemically comparable to ___________, journey activation the what 3 receptors? Anticholinergic - (Acetylcholine) Muscarinic acetylcholine ___________agonist or antagonist?_ uncovered in ________ ... Responsible because that what kind of states?Dissociative anesthetics: _____ agonist or antagonist? and also partial ____ receptor antagonist or agonist?
Classification based on receptor activation:4 main varieties based top top receptor function Serotonergic hallucinogens - Chemically comparable to serotonin - 5HT2a/2c receptor agonists Methylated amphetamines - Chemically comparable to norepinephrine, journey DA, Norepinephrine and 5HT-receptor activation. Anticholinergic - (Acetylcholine) Muscarinic acetylcholine antagonists found in plants: belladonna, mandrake, nutmeg. Responsible for trance or dream-like statesDissociative anesthetics: NMDA antagonist and partial D2 receptor agonist.
Serotonergic hallucinogensChemically comparable to __________ - ________/ receptor agonistsSensory, _________ hallucinations, changed sense the ________Classified together due to _______ - _____ between them (if you take one, you obtain tolerance come another)Creates feeling of _________
Serotonergic hallucinogens Chemically similar to serotonin - 5HT2a/2c receptor agonistsSensory, intuitive hallucinations, transformed sense of timeClassified together because of cross-tolerance between them (if you take it one, you gain tolerance to another)Creates feeling of empathy
Methylated amphetaminesChemically comparable to ____________, journey ___, ____________ and also ______-receptor activation.Drive ____, ______ and also ______ release by binding to __________ and also ___________............. NT pre-synaptically and also binding come the receptor post-synaptically. Alterations in ________ without much readjust in ________
Methylated amphetamines Chemically similar to norepinephrine, journey DA, Norepinephrine and also 5HT-receptor activation.Drive DA, NE and also 5HT relax by binding to transporters and also entering the synapse and also releasing more NT pre-synaptically and also binding to the receptor post-synaptically.Alterations in mood there is no much readjust in senses
Dissociative anesthetics: NMDA __________ and also partial D2 receptor __________Make the so you deserve to remain ___________ in surgery. Reasons ________, numbness, ________ behavior, and _______ _______ disturbances


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Dissociative anesthetics: NMDA antagonist and partial D2 receptor agonist. Do it so you can remain aware in surgery. Reasons euphoria, numbness, wild behavior, and also tactile feeling disturbances